#C070, Recombinant Human IL-1a
Recombinant Human Interleukin-1 Alpha is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed.
- Accession: P01583
- Known As: Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1
- Mol Mass: 18 KDa
- APMol Mass: 17 KDa, reducing conditions
- Endotoxin: Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
- Formulation Description: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
- Purity
Greater than 95% as determined by reducing SDS-PAGE.
- Reconstitution
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Storage
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Shipping
Upon receipt, store it immediately at the temperature listed below.
- Background
Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses.
For Research or Manufacturing Use Only, Not for Use in Diagnostic or Therapeutic Procedures.