Total Solution of Multi-pass Membrane Protein Antibody Drug

Among known drug targets, GPCRs (the largest human receptor family) and ion channels are the most prevalent types, and these two types of targets are also mostly multi-pass membrane proteins. However, the proportion of antibody drugs in these two types of targets is very small, mainly because of the difficulty in developing antibodies for multi-pass membrane targets and the lack of reagents for antibody discovery.

Novoprotein currently provides different forms of antigen products / customised services such as mRNA, multi-pass membrane proteins and overexpression cell lines, which are suitable for animal immunization, antibody screening and verification, quality control and other needs. In addition, we can also provide one-stop technical services from mRNA animal immunization to antibody candidate discovery according to customers' needs, and we have already screened a number of multi-pass membrane protein antibody candidates, such as GPRC5D and Claudin 6, which provide antibody drug of multi-pass membrane protein novel R&D solution.